What is TB-500? TB-500 is commonly described as a research fragment related to thymosin beta-4, a peptide involved in cellular processes associated with migration and tissue repair. Research Areas Cellular migration Angiogenesis research Tissue-repair pathways Wound-healing research Muscle and connective-tissue research Cellular regeneration Why is it being researched? Preclinical research involving thymosin-beta-4-related compounds has examined processes involved in tissue repair, blood-vessel formation and cellular movement. Human evidence for TB-500 specifically remains limited. PRIMAL RESEARCH NOTE: Research evidence for TB-500 is substantially more limited than for approved peptide medicines.